Tucker and Dale are your typical hillbilly rednecks. They are looking to acquire a dilapidated cabin as their new summer home. A group of college students just so happen to be camping near the cabin that Dale and Tucker are interested in. Apparently, the college kids have watched too many scary movies because they accuse the two rednecks of being serial killers. The situation soon turns serious as the students try to take down the rednecks, who are not really killers at all. They are just simple minded country folk.